blueTB pathway: fatty acid synthesis

blueTB pathways

fab

fatty acid biosynthesis

pathway

Click on the pathway overview scheme to view the reactions of a specific branch. blueTB reaction charts are interactive; clicking on a formula brings up a 3D-molecular model of the corresponding structure, clicking on a enzyme name shows its entry in the KEGG Enzyme database. The name of the coding gene is listed in bold on the right side. In case the structure of the corresponding Mycobacterium tuberculosis protein has been solved, the gene name is underlined and its blueTB entry can be accessed by clicking.

part1 | accA | fabD | fab pathway

from acetyl-CoA to malonyl-ACP

activation

elongation cycle

molecules | part 1 | part 2 | fab pathway

enzymes and biochemicals in the fab pathway

Click on a underlined enzyme to go to the description of the corresponding Mycobacterium tuberculosis protein in Dr. PI's blueTB website.

fab part1
- acety-CoA carboxylase, accA
- malonyl CoA:ACP transacylase, fabD
- acyl carrier protein ACP
fab part 2
- β-ketoacyl-ACP synthase, fabH, fabB
- β-hydroxyacyl-ACP reductase, fabG
- β-hydroxycyl-ACP dehydrase, fabA
- enoyl-ACP reductase, fabI, inhA

Click on a biochemical substance name to go to the section on this page, where it is used.

acetyl-S-[]
acyl(C₁₄)-S-[ACP]
acyl(C₁₆)-S-[ACP]
ADP
ATP
CO₂
dihydrogen-phosphate
enoyl(C₁₆)-S-[ACP]
H₂O
hydrogencarbonate
hydroxyacyl(C₁₆)-S-[ACP]
malonyl-S-[]
malonyl-S-[ACP]
NAD
NADH
NADP
NADPH
oxoacyl(C₁₆)-S-[ACP]